Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro

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Document type:: Zeitschriftenaufsatz
Author(s):: Baas, Jennifer ; Bieringer, Sebastian ; Frias, Corazon ; Frias, Jerico ; Soehnchen, Carolina ; Urmann, Corinna ; Ritter, Steffi ; Riepl, Herbert ; Prokop, Aram
Title:: Dihydroxyquingdainone Induces Apoptosis in Leukaemia and Lymphoma Cells via the Mitochondrial Pathway in a Bcl-2- and Caspase-3-Dependent Manner and Overcomes Resistance to Cytostatic Drugs In Vitro
Keywords:: Article ; ; quingdainone ; tryptanthrin ; Nalm-6 ; BJAB ; intrinsic apoptosis pathway
Journal title:: Molecules
Year:: 2022
Journal volume:: 27
Journal issue:: 15
Fulltext / DOI:: doi:10.3390/molecules27155038
Publisher:: MDPI
E-ISSN:: 1420-3049
Date of publication:: 08.08.2022
CC license:: by, https://creativecommons.org/licenses/by/4.0

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