Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model

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Document type:: Zeitschriftenaufsatz
Author(s):: Moustafa, Mohamed ; Dähling, Katarzyna-Krystyna ; Günther, Armin ; Riebandt, Leonie ; Smit, Daniel J. ; Riecken, Kristoffer ; Schröder, Carina ; Zhuang, Ruimeng ; Krech, Till ; Kriegs, Malte ; Fehse, Boris ; Izbicki, Jakob R. ; Fischer, Lutz ; Nashan, Björn ; Li, Jun ; Jücker, Manfred
Title:: Combined Targeting of AKT and mTOR Inhibits Tumor Formation of EpCAM+ and CD90+ Human Hepatocellular Carcinoma Cells in an Orthotopic Mouse Model
Keywords:: Article ; hepatocellular carcinoma ; AKT ; mTOR ; combined treatment ; tumor spheroids ; orthotopic mouse model ; treatment resistance ; EpCAM ; CD90 ; CSC
Journal title:: Cancers
Year:: 2022
Journal volume:: 14
Journal issue:: 8
Fulltext / DOI:: doi:10.3390/cancers14081882
Publisher:: MDPI
E-ISSN:: 2072-6694
Date of publication:: 08.04.2022
CC license:: by, https://creativecommons.org/licenses/by/4.0

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