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Original title:
Macrophage metabolism in N-ERD patients
Translated title:
Makrophagenmetabolismus in N-ERD Patienten
Author:
Bernhardt, Ulrike
Year:
2022
Document type:
Dissertation
Faculty/School:
Fakultät für Medizin
Advisor:
Schmidt-Weber, Carsten (Prof. Dr.)
Referee:
Schmidt-Weber, Carsten (Prof. Dr.); Chaker, Adam (Priv.-Doz. Dr.)
Language:
en
Subject group:
MED Medizin
Keywords:
N-ERD, macrophage
TUM classification:
MED 640
Abstract:
Non-steroidal anti-inflammatory drug (NSAID)- exacerbated respiratory disease is a severe inflammatory condition affecting particularly the airways and nasal sinuses. Macrophages as one of the key players in immune regulation yet have been neglected in N-ERD research. Through our experiments we aimed to reveal differences in aMDM (alveolar-like macrophages) and sMac (sputum macrophages) as well as alterations in body fluids of N-ERD, CRSwNP and healthy subjects. Our results offer a new approach...     »
Translated abstract:
Non-steroidal anti-inflammatory drug (NSAID)- exacerbated respiratory disease ist eine schwerwiegende Atemwegserkrankung. Makrophagen, einer der Hauptakteure der Immunregulation, sind in der N-ERD Forschung vernachlässigt worden. Unsere Experimente sollten Unterschiede zwischen Knochenmarks- und Blutmakrophagen sowie Abweichungen in Köperflüssigkeiten zwischen N-ERD Patienten, Probanden mit CRSwNP und Gesunden aufdecken. Die Ergebnisse könnten neue Ansätze zur Krankheitsentstehung, Diagnoseverfa...     »
WWW:
https://mediatum.ub.tum.de/?id=1633136
Date of submission:
30.11.2021
Oral examination:
21.06.2022
File size:
2217945 bytes
Pages:
107
Urn (citeable URL):
https://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:bvb:91-diss-20220621-1633136-1-7
Last change:
13.10.2022
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