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- Dokumenttyp:
- Journal Article; Comment
- Autor(en):
- Falcomatà, Chiara; Schneider, Günter; Saur, Dieter
- Titel:
- Personalizing KRAS-Mutant Allele-Specific Therapies.
- Abstract:
- KRASG12R mutations occur almost exclusively in pancreatic ductal adenocarcinoma. The results of a study that reveals specific differences in KRAS downstream signaling and metabolic rewiring of pancreatic cancer cells harboring KRASG12R mutations promise to improve our possibilities to better stratify patients for individualized therapies.See related article by Hobbs et al., p. 104.
- Zeitschriftentitel:
- Cancer Discov
- Jahr:
- 2020
- Band / Volume:
- 10
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 23-25
- Volltext / DOI:
- doi:10.1158/2159-8290.CD-19-1261
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/31919121
- Print-ISSN:
- 2159-8274
- TUM Einrichtung:
- II. Medizinische Klinik und Poliklinik (Gastroenterologie); Lehrstuhl für Experimentelle Tumortherapie (Prof. Saur)
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