User: Guest  Login
Document type:
Journal Article 
Author(s):
Baldini, Francesca; Fabbri, Rita; Eberhagen, Carola; Voci, Adriana; Portincasa, Piero; Zischka, Hans; Vergani, Laura 
Title:
Adipocyte hypertrophy parallels alterations of mitochondrial status in a cell model for adipose tissue dysfunction in obesity. 
Abstract:
AIMS: Adipocyte hypertrophy is the main cause of obesity. A deeper understanding of the molecular mechanisms regulating adipocyte dysfunction may help to plan strategies to treat/prevent obesity and its metabolic complications. Here, we investigated in vitro the molecular alterations associated with early adipocyte hypertrophy, focusing on mitochondrial dysfunction. MAIN METHODS: As model of adipocyte hypertrophy, we employed 3T3-L1 preadipocytes firstly differentiated into mature adipocytes, th...    »
 
Journal title abbreviation:
Life Sci 
Year:
2021 
Journal volume:
265 
Print-ISSN:
0024-3205 
TUM Institution:
Institut für Toxikologie und Umwelthygiene