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Document type:
Journal Article; Article 
Author(s):
Müller, Anne; Niederstadt, Lars; Jonas, Wenke; Yi, Chun-Xia; Meyer, Franziska; Wiedmer, Petra; Fischer, Jana; Grötzinger, Carsten; Schürmann, Annette; Tschöp, Matthias; Kleinau, Gunnar; Grüters, Annette; Krude, Heiko; Biebermann, Heike 
Title:
Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling. 
Abstract:
Intact melanocortin signaling via the G protein-coupled receptors (GPCRs), melanocortin receptor 4 (MC4R), and melanocortin receptor 3 (MC3R) is crucial for body weight maintenance. So far, no connection between melanocortin signaling and hypothalamic inflammation has been reported. Using a bimolecular fluorescence complementation library screen, we identified a new interaction partner for these receptors, ring finger protein 11 (RNF11). RNF11 participates in the constitution of the A20 complex...    »
 
Journal title abbreviation:
Front Endocrinol (Lausanne) 
Year:
2016 
Journal volume:
Pages contribution:
109 
Fulltext / DOI:
Print-ISSN:
1664-2392 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)