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Document type:
Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Article 
Author(s):
Tong, J; D'Alessio, D; Ramisch, J; Davis, HW; Stambrook, E; Tschöp, MH; Bidlingmaier, M 
Title:
Ghrelin stimulation of growth hormone isoforms: parallel secretion of total and 20-kDa growth hormone and relation to insulin sensitivity in healthy humans. 
Abstract:
The 20-kDa human GH (hGH) is produced in the pituitary by alternative splicing of the hGH-N gene. The 20-kDa hGH promotes growth similarly to 22-kDa or total hGH, the predominant form in circulation, but the relative effects of these isoforms on glucose metabolism have been debated.To investigate the effect of ghrelin on 20-kDa and total hGH secretion in healthy, nonobese subjects. We also studied associations between basal GH concentration and fasting glucose and insulin as well as between dyna...    »
 
Journal title abbreviation:
J Clin Endocrinol Metab 
Year:
2012 
Journal volume:
97 
Journal issue:
Pages contribution:
3366-74 
Fulltext / DOI:
Print-ISSN:
0021-972X 
TUM Institution:
Kliniken und Institute