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de la Rosa, Jorge;Weber, Julia;Friedrich, Mathias Josef;Li, Yilong;Rad, Lena;Ponstingl, Hannes;Liang, Qi;de Quirós, Sandra Bernaldo;Noorani, Imran;Metzakopian, Emmanouil;Strong, Alexander;Li, Meng Amy;Astudillo, Aurora;Fernández-García, María Teresa;Fernández-García, María Soledad;Hoffman, Gary J;Fuente, Rocío;Vassiliou, George S;Rad, Roland;López-Otín, Carlos;Bradley, Allan;Cadiñanos, Juan
A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes.
Nat Genet
2017
49
5
730-741

Mehr ...

Dovey, Oliver M;Cooper, Jonathan L;Mupo, Annalisa;Grove, Carolyn S;Lynn, Claire;Conte, Nathalie;Andrews, Robert M;Pacharne, Suruchi;Tzelepis, Konstantinos;Vijayabaskar, M S;Green, Paul;Rad, Roland;Arends, Mark;Wright, Penny;Yusa, Kosuke;Bradley, Allan;Varela, Ignacio;Vassiliou, George S
Molecular synergy underlies the co-occurrence patterns and phenotype of -mutant acute myeloid leukemia.
Blood
2017
130
17
1911-1922

Mehr ...

Friedrich, Mathias J;Rad, Lena;Bronner, Iraad F;Strong, Alexander;Wang, Wei;Weber, Julia;Mayho, Matthew;Ponstingl, Hannes;Engleitner, Thomas;Grove, Carolyn;Pfaus, Anja;Saur, Dieter;Cadiñanos, Juan;Quail, Michael A;Vassiliou, George S;Liu, Pentao;Bradley, Allan;Rad, Roland
Genome-wide transposon screening and quantitative insertion site sequencing for cancer gene discovery in mice.
Nat Protoc
2017
12
2
289-309

Mehr ...

Lalremruata, Albert;Jeyaraj, Sankarganesh;Engleitner, Thomas;Joanny, Fanny;Lang, Annika;Bélard, Sabine;Mombo-Ngoma, Ghyslain;Ramharter, Michael;Kremsner, Peter G;Mordmüller, Benjamin;Held, Jana
Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing.
Malar J
2017
16
1
398

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Chapeau, Emilie A;Gembarska, Agnieszka;Durand, Eric Y;Mandon, Emeline;Estadieu, Claire;Romanet, Vincent;Wiesmann, Marion;Tiedt, Ralph;Lehar, Joseph;de Weck, Antoine;Rad, Roland;Barys, Louise;Jeay, Sebastien;Ferretti, Stephane;Kauffmann, Audrey;Sutter, Esther;Grevot, Armelle;Moulin, Pierre;Murakami, Masato;Sellers, William R;Hofmann, Francesco;Jensen, Michael Rugaard
Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf mouse model.
Proc Natl Acad Sci U S A
2017
114
12
3151-3156

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de la Rosa, Jorge;Weber, Julia;Rad, Roland;Bradley, Allan;Cadiñanos, Juan
Disentangling -cooperating tumor suppressor gene networks in cancer.
Mol Cell Oncol
2017
4
4
e1325550

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Yuan, Detian;Huang, Shan;Berger, Emanuel;Liu, Lei;Gross, Nina;Heinzmann, Florian;Ringelhan, Marc;Connor, Tracy O;Stadler, Mira;Meister, Michael;Weber, Julia;Öllinger, Rupert;Simonavicius, Nicole;Reisinger, Florian;Hartmann, Daniel;Meyer, Rüdiger;Reich, Maria;Seehawer, Marco;Leone, Valentina;Höchst, Bastian;Wohlleber, Dirk;Jörs, Simone;Prinz, Marco;Spalding, Duncan;Protzer, Ulrike;Luedde, Tom;Terracciano, Luigi;Matter, Matthias;Longerich, Thomas;Knolle, Percy;Ried, Thomas;Keitel, Verena;Geisler, Fabian;Unger, Kristian;Cinnamon, Einat;Pikarsky, Eli;Hüser, Norbert;Davis, Roger J;Tschaharganeh, Darjus F;Rad, Roland;Weber, Achim;Zender, Lars;Haller, Dirk;Heikenwälder, Mathias
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.
Cancer Cell
2017
31
6
771-789.e6

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Wartewig, Tim;Kurgyis, Zsuzsanna;Keppler, Selina;Pechloff, Konstanze;Hameister, Erik;Öllinger, Rupert;Maresch, Roman;Buch, Thorsten;Steiger, Katja;Winter, Christof;Rad, Roland;Ruland, Jürgen
PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis.
Nature
2017
552
7683
121-125

Mehr ...

Schneider, Günter;Schmidt-Supprian, Marc;Rad, Roland;Saur, Dieter
Tissue-specific tumorigenesis: context matters.
Nat Rev Cancer
2017
17
4
239-253