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Document type:
Journal Article; Article 
Renner, Simone; Blutke, Andreas; Dobenecker, Britta; Dhom, Georg; Müller, Timo D; Finan, Brian; Clemmensen, Christoffer; Bernau, Maren; Novak, Istvan; Rathkolb, Birgit; Senf, Steffanie; Zöls, Susanne; Roth, Mirjam; Götz, Anna; Hofmann, Susanna M; Hrab? de Angelis, Martin; Wanke, Rüdiger; Kienzle, Ellen; Scholz, Armin M; DiMarchi, Richard; Ritzmann, Mathias; Tschöp, Matthias H; Wolf, Eckhard 
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs. 
The worldwide prevalence of obesity has increased to 10% in men and 15% in women and is associated with severe comorbidities such as diabetes, cancer, and cardiovascular disease. Animal models of obesity are central to experimental studies of disease mechanisms and therapeutic strategies. Diet-induced obesity (DIO) models in rodents have provided important insights into the pathophysiology of obesity and, in most instances, are the first in line for exploratory pharmacology studies. To deepen th...    »
Journal title abbreviation:
Mol Metab 
Journal volume:
Pages contribution:
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)