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- Document type:
- Review; Journal Article; Meta-Analysis; Systematic Review
- Author(s):
- Glöckl, R; Schneeberger, T; Boeselt, T; Kenn, K; Koczulla, A R; Held, M; Oberhoffer, R; Halle, M
- Title:
- [Exercise Training in Patients with Pulmonary Hypertension: A Systematic Review and Meta-analysis].
- Abstract:
- BACKGROUND: Pulmonary hypertension (PH) is defined as an elevation of mean pulmonary-arterial pressure by > 20 mmHg at rest, which may lead to right heart failure. Physical exercise has not been regularly recommended for PH patients for fear of symptom deterioration or occurrence of exercise-induced adverse events. METHODS: Three electronic databases were searched for randomized, controlled trials investigating exercise training in PH patients using the following keywords: "pulmonary hypertension" OR "pulmonary arterial hypertension" AND "exercise" OR "pulmonary rehabilitation" AND "randomized". RESULTS: Five studies involving 187 PH patients were included in this systematic review. Exercise programs lasted for 3 - 12 weeks (e. g. endurance training for 10 - 45 minutes; 60 - 80 % of the peak heart rate). PH patients significantly improved exercise capacity compared to controls in 6-minute walk distance (+ 45 m; 95 % CI: 26 m - 64 m) or peak oxygen consumption (+ 2.3 ml/kg/min; 95 % CI: 1.8 - 2.9 ml/kg/min), both p < 0.001. Also, physical and mental quality of life improved significantly by exercise training. No exercise-induced adverse events were observed. CONCLUSION: Supervised exercise training can safely and significantly improve physical performance and quality of life in clinically stable PH patients with optimal drug treatment. However, larger studies including a wider range of PH are mandatory.
- Journal title abbreviation:
- Pneumologie
- Year:
- 2019
- Journal volume:
- 73
- Journal issue:
- 11
- Pages contribution:
- 677-685
- Fulltext / DOI:
- doi:10.1055/a-1005-8678
- Pubmed ID:
- http://view.ncbi.nlm.nih.gov/pubmed/31715636
- Print-ISSN:
- 0934-8387
- TUM Institution:
- Poliklinik für Präventive und Rehabilitative Sportmedizin
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