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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Specht, S; Frank, JK; Alferink, J; Dubben, B; Layland, LE; Denece, G; Bain, O; Förster, I; Kirschning, CJ; Martin, C; Hoerauf, A 
Title:
CCL17 controls mast cells for the defense against filarial larval entry. 
Abstract:
Filarial parasites have to trespass many barriers to successfully settle within their mammalian host, which is equipped with mechanical borders and complex weaponry of an evolved immune system. However, little is known about mechanisms of early local events in filarial infections. In this study, bone marrow-derived dendritic cells not only upregulated activation markers CD40 and CD80 upon in vitro stimulation with filarial extracts, but also secreted CCL17, a chemokine known to be produced upon...    »
 
Journal title abbreviation:
J Immunol 
Year:
2011 
Journal volume:
186 
Journal issue:
Pages contribution:
4845-52 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0022-1767 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene