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Nystoriak, Matthew A;Nieves-Cintrón, Madeline;Patriarchi, Tommaso;Buonarati, Olivia R;Prada, Maria Paz;Morotti, Stefano;Grandi, Eleonora;Fernandes, Julia Dos Santos;Forbush, Katherine;Hofmann, Franz;Sasse, Kent C;Scott, John D;Ward, Sean M;Hell, Johannes W;Navedo, Manuel F
Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes.
Sci Signal
2017
10
463

Mehr ...

Qian, Hai;Patriarchi, Tommaso;Price, Jennifer L;Matt, Lucas;Lee, Boram;Nieves-Cintrón, Madeline;Buonarati, Olivia R;Chowdhury, Dhrubajyoti;Nanou, Evanthia;Nystoriak, Matthew A;Catterall, William A;Poomvanicha, Montatip;Hofmann, Franz;Navedo, Manuel F;Hell, Johannes W
Phosphorylation of Ser1928 mediates the enhanced activity of the L-type Ca2+ channel Cav1.2 by the ?2-adrenergic receptor in neurons.
Sci Signal
2017
10
463

Mehr ...

Schinner, Elisabeth;Wetzl, Veronika;Schramm, Andrea;Kees, Frieder;Sandner, Peter;Stasch, Johannes-Peter;Hofmann, Franz;Schlossmann, Jens
Inhibition of the TGF? signalling pathway by cGMP and cGMP-dependent kinase I in renal fibrosis.
FEBS Open Bio
2017
7
4
550-561

Mehr ...

Collado-Alsina, Andrea;Hofmann, Franz;Sánchez-Prieto, José;Torres, Magdalena
Altered Synaptic Membrane Retrieval after Strong Stimulation of Cerebellar Granule Neurons in Cyclic GMP-Dependent Protein Kinase II (cGKII) Knockout Mice.
Int J Mol Sci
2017
18
11

Mehr ...

Wang, Rui;Islam, Bianca N;Bridges, Allison;Sharman, Sarah K;Hu, Muhan;Hou, Yali;Somanath, Payaningal R;Venable, Laine;Singh, Nagendra;Kim, Sangmi;Sridhar, Subbaramiah;Hofmann, Franz;Browning, Darren D
cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium.
Am J Pathol
2017
187
2
377-389

Mehr ...

Hinz, Laura;Ahles, Andrea;Ruprecht, Benjamin;Kuster, Bernhard;Engelhardt, Stefan
Two serines in the distal C-terminus of the human ß1-adrenoceptor determine ß-arrestin2 recruitment.
PLoS ONE
2017
12
5
e0176450

Mehr ...

Werfel, Stanislas;Leierseder, Simon;Ruprecht, Benjamin;Kuster, Bernhard;Engelhardt, Stefan
Preferential microRNA targeting revealed by in vivo competitive binding and differential Argonaute immunoprecipitation.
Nucleic Acids Res
2017
45
17
10218-10228

Mehr ...

Wang, Jialu;Hanada, Kenji;Staus, Dean P;Makara, Michael A;Dahal, Giri Raj;Chen, Qiang;Ahles, Andrea;Engelhardt, Stefan;Rockman, Howard A
G? is required for carvedilol-induced ? adrenergic receptor ?-arrestin biased signaling.
Nat Commun
2017
8
1
1706

Mehr ...

Sassi, Yassine;Avramopoulos, Petros;Ramanujam, Deepak;Grüter, Laurenz;Werfel, Stanislas;Giosele, Simon;Brunner, Andreas-David;Esfandyari, Dena;Papadopoulou, Aikaterini S;De Strooper, Bart;Hübner, Norbert;Kumarswamy, Regalla;Thum, Thomas;Yin, Xiaoke;Mayr, Manuel;Laggerbauer, Bernhard;Engelhardt, Stefan
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling.
Nat Commun
2017
8
1
1614

Mehr ...

Toischer, Karl;Zhu, Wuqiang;Hünlich, Mark;Mohamed, Belal A;Khadjeh, Sara;Reuter, Sean P;Schäfer, Katrin;Ramanujam, Deepak;Engelhardt, Stefan;Field, Loren J;Hasenfuss, Gerd
Cardiomyocyte proliferation prevents failure in pressure overload but not volume overload.
J Clin Invest
2017
127
12
4285-4296