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Titel:

Mitochondria and Reactive Oxygen Species in Aging and Age-Related Diseases.

Dokumenttyp:
Journal Article
Autor(en):
Giorgi, Carlotta; Marchi, Saverio; Simões, Inês C M; Ren, Ziyu; Morciano, Giampaolo; Perrone, Mariasole; Patalas-Krawczyk, Paulina; Borchard, Sabine; J?drak, Paulina; Pierzynowska, Karolina; Szyma?ski, J?drzej; Wang, David Q; Portincasa, Piero; W?grzyn, Grzegorz; Zischka, Hans; Dobrzyn, Pawel; Bonora, Massimo; Duszynski, Jerzy; Rimessi, Alessandro; Karkucinska-Wieckowska, Agnieszka; Dobrzyn, Agnieszka; Szabadkai, Gyorgy; Zavan, Barbara; Oliveira, Paulo J; Sardao, Vilma A; Pinton, Paolo; Wieckows...     »
Abstract:
Aging has been linked to several degenerative processes that, through the accumulation of molecular and cellular damage, can progressively lead to cell dysfunction and organ failure. Human aging is linked with a higher risk for individuals to develop cancer, neurodegenerative, cardiovascular, and metabolic disorders. The understanding of the molecular basis of aging and associated diseases has been one major challenge of scientific research over the last decades. Mitochondria, the center of oxid...     »
Zeitschriftentitel:
Int Rev Cell Mol Biol
Jahr:
2018
Band / Volume:
340
Seitenangaben Beitrag:
209-344
Sprache:
eng
Volltext / DOI:
doi:10.1016/bs.ircmb.2018.05.006
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/30072092
Print-ISSN:
1937-6448
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene
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