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Document type:
journal article 
Author(s):
Alessandrini, Francesca; Vennemann, Antje; Gschwendtner, Silvia; Neumann, Avidan U; Rothballer, Michael; Seher, Tanja; Wimmer, Maria; Kublik, Susanne; Traidl-Hoffmann, Claudia; Schloter, Michael; Wiemann, Martin; Schmidt-Weber, Carsten B 
Title:
Pro-Inflammatory versus Immunomodulatory Effects of Silver Nanoparticles in the Lung: The Critical Role of Dose, Size and Surface Modification. 
Abstract:
The growing use of silver nanoparticles (Ag-NPs) in consumer products raises concerns about their toxicological potential. The purpose of the study was to investigate the size- and coating-dependent pulmonary toxicity of Ag-NPs in vitro and in vivo, using an ovalbumin (OVA)-mouse allergy model. Supernatants from (5.6-45 µg/mL) Ag50-PVP, Ag200-PVP or Ag50-citrate-treated NR8383 alveolar macrophages were tested for lactate dehydrogenase and glucuronidase activity, tumor necrosis factor (TNF)-? rel...    »
 
Journal title abbreviation:
Nanomaterials (Basel) 
Year:
2017 
Journal volume:
Journal issue:
10 
Language:
eng 
Print-ISSN:
2079-4991 
TUM Institution:
Institut für Molekulare Allergologie