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Document type:
journal article 
Author(s):
Kruger, Stephan; Legenstein, Marie-Louise; Rösgen, Verena; Haas, Michael; Modest, Dominik Paul; Westphalen, Christoph Benedikt; Ormanns, Steffen; Kirchner, Thomas; Heinemann, Volker; Holdenrieder, Stefan; Boeck, Stefan 
Title:
Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer. 
Abstract:
Up to now, the efficacy of programmed death protein 1/programmed death ligand 1 (PD-1/PD-L1) blockade in pancreatic cancer (PC) remains uncertain. Serum levels of soluble PD-1 and PD-L1 (sPD-1/sPD-L1) have been reported to be independent prognostic factors in solid tumors susceptible to checkpoint blockade. Provenience, regulation and immunologic function of sPD-1 and sPD-L1 in cancer are poorly understood. To the best of our knowledge, sPD-1 and sPD-L1 have not been measured conjointly in any c...    »
 
Journal title abbreviation:
Oncoimmunology 
Year:
2017 
Journal volume:
Journal issue:
Pages contribution:
e1310358 
Language:
eng 
Print-ISSN:
2162-4011 
TUM Institution:
Institut für Laboratoriumsmedizin