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Document type:
journal article 
Author(s):
Nieberler, M; Reuning, U; Kessler, H; Reichart, F; Weirich, G; Wolff, K-D 
Title:
Fluorescence imaging of invasive head and neck carcinoma cells with integrin ?v?6-targeting RGD-peptides: an approach to a fluorescence-assisted intraoperative cytological assessment of bony resection margins. 
Abstract:
We assessed the use of peptides containing arginylglycylaspartic acid (RGD) that target integrin ?v?6 as a potential approach for a fluorescence-assisted intraoperative cytological assessment of bony resection margins (F-AICAB) in patients who had bone-infiltrating squamous cell carcinoma (SCC) of the head and neck. This was assessed to demarcate invasive carcinoma cells that stained for ?v?6. Specimens from bony resection margins (n=362) were defined as either malignant or benign according to t...    »
 
Journal title abbreviation:
Br J Oral Maxillofac Surg 
Year:
2018 
Journal volume:
56 
Journal issue:
10 
Pages contribution:
972-978 
Language:
eng 
Print-ISSN:
0266-4356 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie