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Document type:
journal article 
Author(s):
Zimmermann, K; Hossann, M; Hirschberger, J; Troedson, K; Peller, M; Schneider, M; Bruhschwein, A; Meyer-Lindenberg, A; Wess, G; Wergin, M; Dorfelt, R; Knosel, T; Schwaiger, M; Baumgartner, C; Brandl, J; Schwamberger, S; Lindner, LH 
Title:
A pilot trial of doxorubicin containing phosphatidyldiglycerol based thermosensitive liposomes in spontaneous feline soft tissue sarcoma 
Abstract:
Purpose: Doxorubicin (DOX)-loaded phosphatidyldiglycerol-based thermosensitive liposomes (DPPG(2)-TSL-DOX) combined with local hyperthermia (HT) was evaluated in cats with locally advanced spontaneous fibrosarcomas (soft tissue sarcoma [STS]). The study was designed to evaluate the safety and pharmacokinetic profile of the drug. Results from four dose-levels are reported.Methods: Eleven client-owned cats with advanced STS were enrolled. Five cats received escalating doses of 0.1-0.4mg/kg DOX (gr...    »
 
Journal title abbreviation:
Int J Hyperthermia 
Year:
2017 
Journal volume:
33 
Journal issue:
Pages contribution:
178-190 
Language:
eng 
Print-ISSN:
0265-6736 
TUM Institution:
Fakultät für Medizin (Medizindidaktik, TUMCells, ZPF, MSZ; Profs. Tschöp bis 2015)