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Document type:
journal article 
Author(s):
Kälin, Stefanie; Heppner, Frank L; Bechmann, Ingo; Prinz, Marco; Tschöp, Matthias H; Yi, Chun-Xia 
Title:
Hypothalamic innate immune reaction in obesity. 
Abstract:
Findings from rodent and human studies show that the presence of inflammatory factors is positively correlated with obesity and the metabolic syndrome. Obesity-associated inflammatory responses take place not only in the periphery but also in the brain. The hypothalamus contains a range of resident glial cells including microglia, macrophages and astrocytes, which are embedded in highly heterogenic groups of neurons that control metabolic homeostasis. This complex neural-glia network can receive...    »
 
Journal title abbreviation:
Nat Rev Endocrinol 
Year:
2015 
Journal volume:
11 
Journal issue:
Pages contribution:
339-51 
Language:
eng 
Print-ISSN:
1759-5029 
TUM Institution:
Fakultät für Medizin (zentral angehängte Professuren und Einrichtungen: Profs. Tschöp, Berberat; TUMCells, ZPF, MSZ)