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Document type:
journal article 
Author(s):
Burger, Karin; Ilicic, Katarina; Dierolf, Martin; Günther, Benedikt; Walsh, Dietrich W M; Schmid, Ernst; Eggl, Elena; Achterhold, Klaus; Gleich, Bernhard; Combs, Stephanie E; Molls, Michael; Schmid, Thomas E; Pfeiffer, Franz; Wilkens, Jan J 
Title:
Increased cell survival and cytogenetic integrity by spatial dose redistribution at a compact synchrotron X-ray source. 
Abstract:
X-ray microbeam radiotherapy can potentially widen the therapeutic window due to a geometrical redistribution of the dose. However, high requirements on photon flux, beam collimation, and system stability restrict its application mainly to large-scale, cost-intensive synchrotron facilities. With a unique laser-based Compact Light Source using inverse Compton scattering, we investigated the translation of this promising radiotherapy technique to a machine of future clinical relevance. We performe...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2017 
Journal volume:
12 
Journal issue:
10 
Pages contribution:
e0186005 
Language:
eng 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Institut für Diagnostische und Interventionelle Radiologie