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Document type:
journal article 
Author(s):
Steinacker, Petra; Semler, Elisa; Anderl-Straub, Sarah; Diehl-Schmid, Janine; Schroeter, Matthias L; Uttner, Ingo; Foerstl, Hans; Landwehrmeyer, Bernhard; von Arnim, Christine A F; Kassubek, Jan; Oeckl, Patrick; Huppertz, Hans-Jürgen; Fassbender, Klaus; Fliessbach, Klaus; Prudlo, Johannes; Roßmeier, Carola; Kornhuber, Johannes; Schneider, Anja; Volk, Alexander E; Lauer, Martin; Danek, Adrian; Ludolph, Albert C; Otto, Markus; FTLDc Study Group 
Title:
Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias. 
Abstract:
To assess the utility of serum neurofilament for diagnosis and monitoring of primary progressive aphasia (PPA) variants.We investigated neurofilament light chain (NF-L) levels in blood of 99 patients with PPA (40 with nonfluent variant PPA [nfvPPA], 38 with semantic variant PPA [svPPA], 21 with logopenic variant PPA [lvPPA]) and compared diagnostic performance with that reached by CSF NF-L, phosphorylated neurofilament heavy chain (pNF-H), ?-amyloid (A?), tau, and phosphorylated tau. The longitu...    »
 
Journal title abbreviation:
Neurology 
Year:
2017 
Journal volume:
88 
Journal issue:
10 
Pages contribution:
961-969 
Language:
eng 
Print-ISSN:
0028-3878 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie