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Dokumenttyp:
journal article 
Autor(en):
Koley, AP; Buters, JT; Robinson, RC; Markowitz, A; Friedman, FK 
Titel:
Interaction of polycyclic aromatic hydrocarbons with human cytochrome P450 1A1: a CO flash photolysis study. 
Abstract:
The kinetics of CO binding to human cytochrome P450 1A1 was used to probe the interaction of polycyclic aromatic hydrocarbons (PAHs) with the membrane-bound P450 expressed in baculovirus-infected SF9 insect cells. Biexponential kinetics was observed, indicating that P450 1A1 is composed of at least two kinetically distinguishable species. To define the substrate specificity of the individual species, we evaluated the effect of a series of PAHs of varying sizes and shapes on the CO binding kineti...    »
 
Zeitschriftentitel:
Arch Biochem Biophys 
Jahr:
1996 
Band / Volume:
336 
Heft / Issue:
Seitenangaben Beitrag:
261-7 
Sprache:
eng 
Print-ISSN:
0003-9861 
TUM Einrichtung:
r Molekulare Allergologie und Umweltforschung