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Document type:
journal article 
Author(s):
Yu, M; Nekolla, SG; Schwaiger, M; Robinson, SP 
Title:
The next generation of cardiac positron emission tomography imaging agents: discovery of flurpiridaz F-18 for detection of coronary disease. 
Abstract:
Myocardial perfusion imaging (MPI) with thallium 201 ((201)Tl) or (99m)Tc based imaging agents has become a major tool for noninvasive identification of coronary artery disease (CAD). However, single photon emission computed tomography (SPECT) imaging with the current agents is vulnerable to artifacts associated with soft tissue attenuation, proximal gastrointestinal activity, image quality, and suboptimal sensitivity and is limited by the degree of first-pass myocardial extraction. The developm...    »
 
Journal title abbreviation:
Semin Nucl Med 
Year:
2011 
Journal volume:
41 
Journal issue:
Pages contribution:
305-13 
Language:
eng 
Print-ISSN:
0001-2998 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik