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Document type:
journal article 
Author(s):
Rainov, NG; Zimmer, C; Chase, M; Kramm, CM; Chiocca, EA; Weissleder, R; Breakefield, XO 
Title:
Selective uptake of viral and monocrystalline particles delivered intra-arterially to experimental brain neoplasms. 
Abstract:
In this study we investigated the intra-arterial delivery of viral and nonviral particles to experimental brain tumors. A herpes simplex virus (HSV) vector and monocrystalline iron oxide nanoparticles (MION) were injected into the internal carotid artery of Fisher 344 rats harboring intracerebral 9L gliosarcomas, using bradykinin to disrupt the blood-tumor barrier. Brain and internal organs were stained both for virus-mediated gene expression and for iron. Quantitative comparisons of gene expres...    »
 
Journal title abbreviation:
Hum Gene Ther 
Year:
1995 
Journal volume:
Journal issue:
12 
Pages contribution:
1543-52 
Language:
eng 
Print-ISSN:
1043-0342 
TUM Institution:
Abteilung für Neuroradiologie