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Document type:
journal article 
Author(s):
Hultström, AL; Bratt, G; Cosma, A; Erfle, V; Wahren, B; Carbone, E 
Title:
Autologous cytotoxicity of natural killer cells derived from HIV-infected patients. 
Abstract:
NK cells recognize target cells with reduced expression of MHC class I molecules. Human immunodeficiency virus (HIV) infection decreases MHC class I on the cell membrane. The aim of this study was to directly evaluate the role and conditions of NK cell effects in HIV seropositive patients ex vivo. Autologous HIV-infected CD4+ T cells were exposed to NK cells recognition. We discovered an increased lysis of the target cells after infection with human immunodeficiency virus-1 (HIV-1). The expressi...    »
 
Journal title abbreviation:
Immunol Lett 
Year:
2004 
Journal volume:
91 
Journal issue:
2-3 
Pages contribution:
155-8 
Language:
eng 
Print-ISSN:
0165-2478 
TUM Institution:
Institut für Virologie