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Document type:
journal article 
Author(s):
Cosma, A; Bühler, S; Nagaraj, R; Staib, C; Hammarin, AL; Wahren, B; Goebel, FD; Erfle, V; Sutter, G 
Title:
Neutralization assay using a modified vaccinia virus Ankara vector expressing the green fluorescent protein is a high-throughput method to monitor the humoral immune response against vaccinia virus. 
Abstract:
Vaccination against smallpox is again considered in order to face a possible bioterrorist threat, but the nature and the level of the immune response needed to protect a person from smallpox after vaccination are not totally understood. Therefore, simple, rapid, and accurate assays to evaluate the immune response to vaccinia virus need to be developed. Neutralization assays are usually considered good predictors of vaccine efficacy and more informative with regard to protection than binding assa...    »
 
Journal title abbreviation:
Clin Diagn Lab Immunol 
Year:
2004 
Journal volume:
11 
Journal issue:
Pages contribution:
406-10 
Language:
eng 
Print-ISSN:
1071-412X 
TUM Institution:
Institut für Virologie