User: Guest  Login
Document type:
journal article 
Author(s):
Massberg, S; Gawaz, M; Grüner, S; Schulte, V; Konrad, I; Zohlnhöfer, D; Heinzmann, U; Nieswandt, B 
Title:
A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo. 
Abstract:
Platelet adhesion and aggregation at sites of vascular injury is crucial for hemostasis but may lead to arterial occlusion in the setting of atherosclerosis and precipitate diseases such as myocardial infarction. A current hypothesis suggests that platelet glycoprotein (GP) Ib interaction with von Willebrand factor recruits flowing platelets to the injured vessel wall, where subendothelial fibrillar collagens support their firm adhesion and activation. However, so far this hypothesis has not bee...    »
 
Journal title abbreviation:
J Exp Med 
Year:
2003 
Journal volume:
197 
Journal issue:
Pages contribution:
41-9 
Language:
eng 
Print-ISSN:
0022-1007 
TUM Institution:
I. Medizinische Klinik und Poliklinik