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Document type:
journal article 
Author(s):
Ueblacker, P; Wagner, B; Krüger, A; Vogt, S; DeSantis, G; Kennerknecht, E; Brill, T; Hillemanns, M; Salzmann, GM; Imhoff, AB; Plank, C; Gänsbacher, B; Martinek, V 
Title:
Inducible nonviral gene expression in the treatment of osteochondral defects. 
Abstract:
OBJECTIVE: The repair of osteochondral defects with chondrocytes genetically modified to express desired growth factors promises great potential in orthopaedic therapy. Controlled expression of the transgenes is required in many instances. The objective of the present study was to demonstrate the inducibility of tetracycline-responsive transgene expression in osteochondral defects in the knee joint filled with genetically modified chondrocyte implants. METHODS: An expression plasmid containing t...    »
 
Journal title abbreviation:
Osteoarthritis Cartilage 
Year:
2004 
Journal volume:
12 
Journal issue:
Pages contribution:
711-9 
Language:
eng 
Print-ISSN:
1063-4584 
TUM Institution:
die; r experimentelle Onkologie und Therapieforschung