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Document type:
journal article 
Author(s):
Schulze, J; Voss, S; Zissler, U; Rose, MA; Zielen, S; Schubert, R 
Title:
Airway responses and inflammation in subjects with asthma after four days of repeated high-single-dose allergen challenge. 
Abstract:
ABSTRACT:Both standard and low-dose allergen provocations are an established tool in asthma research to improve our understanding of the pathophysiological mechanism of allergic asthma. However, clinical symptoms are less likely to be induced. Therefore, we designed a protocol for repetitive high-dose bronchial allergen challenges to generate clinical symptoms and airway inflammation.A total of 27 patients aged 18 to 40 years with positive skin-prick tests and mild asthma underwent repetitive hi...    »
 
Journal title abbreviation:
Respir Res 
Year:
2012 
Journal volume:
13 
Pages contribution:
78 
Language:
eng 
Print-ISSN:
1465-9921 
TUM Institution:
r Molekulare Allergologie und Umweltforschung