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Document type:
journal article 
Author(s):
Simon, D; Von Gunten, S; Borelli, S; Braathen, LR; Simon, HU 
Title:
The interleukin-13 production by peripheral blood T cells from atopic dermatitis patients does not require CD2 costimulation. 
Abstract:
BACKGROUND: Although allergic mechanisms appear to be important, the pathogenesis of both extrinsic and intrinsic forms of atopic dermatitis (AD) is unknown. METHODS: We compared the cytokine production of peripheral blood mononuclear cells of extrinsic AD (EAD) and intrinsic AD (IAD) patients and normal control individuals after stimulation with anti-CD3 and/or anti-CD28 monoclonal antibodies (mAbs) in the presence or absence of anti-CD2-blocking mAb. The cytokine production was measured by imm...    »
 
Journal title abbreviation:
Int Arch Allergy Immunol 
Year:
2003 
Journal volume:
132 
Journal issue:
Pages contribution:
148-55 
Language:
eng 
Print-ISSN:
1018-2438 
TUM Institution:
r Dermatologie und Allergologie