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Document type:
journal article 
Author(s):
Eberspächer, E; Heimann, K; Hollweck, R; Werner, C; Schneider, G; Engelhard, K 
Title:
The effect of electroencephalogram-targeted high- and low-dose propofol infusion on histopathological damage after traumatic brain injury in the rat. 
Abstract:
BACKGROUND: Propofol is commonly used to sedate patients after traumatic brain injury. However, the dose-dependent neuroprotective effects of propofol after head trauma are unknown. We compared histopathological damage after 6 h of electroencephalogram-targeted high- and low-dose propofol infusion in rats subjected to controlled cortical impact (CCI). METHODS: Animals were randomly assigned to CCI/propofol with electroencephalogram burst-suppression-ratio 1%-5% (CCI/lowprop), CCI/propofol with b...    »
 
Journal title abbreviation:
Anesth Analg 
Year:
2006 
Journal volume:
103 
Journal issue:
Pages contribution:
1527-33 
Language:
eng 
Print-ISSN:
0003-2999 
TUM Institution:
sthesiologie; r Medizinische Statistik und Epidemiologie