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Autor(en):
Blobel, C. P.; Wolfsberg, T. G.; Turck, C. W.; Myles, D. G.; Primakoff, P.; White, J. M. 
Titel:
A potential fusion peptide and an integrin ligand domain in a protein active in sperm-egg fusion 
Abstract:
The union of sperm and egg is a special membrane fusion event that gives a signal to begin development. We have hypothesized that proteins mediating cell-cell fusion events resemble viral fusion proteins and have shown that PH-30, a sperm surface protein involved in sperm-egg fusion, shares biochemical characteristics with viral fusion proteins. We report here the complementary DNA and deduced amino-acid sequences of the mature alpha and beta subunits of PH-30. Both are type-I integral membrane...    »
 
Zeitschriftentitel:
Nature 
Jahr:
1992 
Band / Volume:
356 
Heft / Issue:
6366 
Seitenangaben Beitrag:
248--252 
Print-ISSN:
0028-0836