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Document type:
journal article 
Author(s):
Santarelli, S; Wagner, K V; Labermaier, C; Uribe, A; Dournes, C; Balsevich, G; Hartmann, J; Masana, M; Holsboer, F; Chen, A; Müller, M B; Schmidt, M V 
Title:
SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system. 
Abstract:
Major depression is a multifactorial disease, involving both environmental and genetic risk factors. Recently, SLC6A15 - a neutral amino acid transporter mainly expressed in neurons - was proposed as a new candidate gene for major depression and stress vulnerability. Risk allele carriers for a single nucleotide polymorphism (SNP) in a SLC6A15 regulatory region display altered hippocampal volume, glutamate levels, and hypothalamus-pituitary-adrenal axis activity, all markers associated with major...    »
 
Journal title abbreviation:
Stress 
Year:
2016 
Journal volume:
19 
Journal issue:
Pages contribution:
83-90 
Language:
eng 
Print-ISSN:
1025-3890 
TUM Institution:
Institut für Neurowissenschaften