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Document type:
journal article 
Author(s):
Knier, Benjamin; Berthele, Achim; Buck, Dorothea; Schmidt, Paul; Zimmer, Claus; Mühlau, Mark; Hemmer, Bernhard; Korn, Thomas 
Title:
Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination. 
Abstract:
Establishing biomarkers for predicting disease activity in demyelinating disease of the central nervous system is crucial for designing appropriate disease modifiying treatment strategies.To investigate retinal findings and disease activity in patients with radiologically isolated and clinically isolated syndromes.We performed retinal optical coherence tomography and cerebral magnetic resonance imaging in healthy control individuals (n=19), in individuals with non-specific white matter lesions (...    »
 
Journal title abbreviation:
Mult Scler 
Year:
2016 
Journal volume:
22 
Journal issue:
Pages contribution:
893-900 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1352-4585 
TUM Institution:
Lehrstuhl für Molekulare Neuroimmunologie; Neurologische Klinik und Poliklinik; Abteilung für Neuroradiologie