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Document type:
journal article 
Author(s):
Stiel, Andre C; Deán-Ben, Xosé Luís; Jiang, Yuanyuan; Ntziachristos, Vasilis; Razansky, Daniel; Westmeyer, Gil G 
Title:
High-contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic tomography. 
Abstract:
Photocontrol of reversibly switchable fluorescent proteins (RSFPs) was used to program optoacoustic signal time courses that were temporally unmixed to increase the proteins' contrast-to-noise-ratios (CNRs) in optoacoustic imaging. In this way, two variants of the RSFP Dronpa with very similar optoacoustic spectra could be readily discriminated in the presence of highly absorbing blood. Addition of temporal unmixing to multispectral optoacoustic tomography (tuMSOT) in conjunction with synthetic...    »
 
Journal title abbreviation:
Opt Lett 
Year:
2015 
Journal volume:
40 
Journal issue:
Pages contribution:
367-70 
Language:
eng 
Print-ISSN:
0146-9592 
TUM Institution:
Lehrstuhl für Biologische Bildgebung; Nuklearmedizinische Klinik und Poliklinik