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Document type:
journal article 
Author(s):
Krüger, Achim 
Title:
Premetastatic niche formation in the liver: emerging mechanisms and mouse models. 
Abstract:
The liver is recognized as the target organ of metastases of almost all prominent malignancies. Its unique biology renders this organ particularly susceptible to circulating disseminated tumour cells (DTCs), and it can be assumed that very early metastasis occurs in the liver. The premetastatic niche concept may explain very early metastasis, as it defines priming of a future target organ of metastasis by factors that may already be secreted from premalignant lesions. This review shows that comp...    »
 
Journal title abbreviation:
J Mol Med 
Year:
2015 
Journal volume:
93 
Journal issue:
11 
Pages contribution:
1193-201 
Language:
eng 
Print-ISSN:
0946-2716 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung