User: Guest  Login
Document type:
journal article 
Author(s):
Bürck, Carolin; Mund, Andreas; Berscheminski, Julia; Kieweg, Lisa; Müncheberg, Sarah; Dobner, Thomas; Schreiner, Sabrina 
Title:
KAP1 Is a Host Restriction Factor That Promotes Human Adenovirus E1B-55K SUMO Modification. 
Abstract:
Once transported to the replication sites, human adenoviruses (HAdVs) need to ensure decondensation and transcriptional activation of their viral genomes to synthesize viral proteins and initiate steps to reprogram the host cell for viral replication. These early stages during adenoviral infection are poorly characterized but represent a decisive moment in the establishment of a productive infection. Here, we identify a novel host viral restriction factor, KAP1. This heterochromatin-associated t...    »
 
Journal title abbreviation:
J Virol 
Year:
2015 
Journal volume:
90 
Journal issue:
Pages contribution:
930-46 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Institut für Virologie