User: Guest  Login
Document type:
journal article 
Author(s):
Goetze, Kristina; Fabian, Christian G; Siebers, Andrea; Binz, Livia; Faber, Daniel; Indraccolo, Stefano; Nardo, Giorgia; Sattler, Ulrike G A; Mueller-Klieser, Wolfgang 
Title:
Manipulation of tumor metabolism for therapeutic approaches: ovarian cancer-derived cell lines as a model system. 
Abstract:
Malignant transformation of cells is often accompanied by up-regulation of glycolysis-related enzymes and transporters, as well as a distortion of mitochondrial respiration. As a consequence, most malignant tumors utilize high amounts of glucose and produce and accumulate high concentrations of lactate, even in the presence of oxygen. This phenomenon has been termed'Warburg Effect'. Here, we aimed at resolving the interrelation between tumor metabolism, reactive oxygen species, double strand DNA...    »
 
Journal title abbreviation:
Cell Oncol (Dordr) 
Year:
2015 
Journal volume:
38 
Journal issue:
Pages contribution:
377-85 
Language:
eng 
Print-ISSN:
2211-3428 
TUM Institution:
III. Medizinische Klinik und Poliklinik