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Document type:
journal article 
Author(s):
Preis, Laura; Herlemann, Annika; Adam, Rosalyn M; Dietz, Hans-Georg; Kappler, Roland; Stehr, Maximilian 
Title:
Platelet Derived Growth Factor Has a Role in Pressure Induced Bladder Smooth Muscle Cell Hyperplasia and Acts in a Paracrine Way. 
Abstract:
Bladder outlet obstruction is a finding in many urological disorders, leading to bladder wall hyperplasia. We investigated platelet derived growth factor and its receptor in human bladder smooth muscle cells and urothelial cells exposed to hydrostatic pressure or PDGF in vitro.Bladder smooth muscle cells and urothelial cells were exposed to elevated hydrostatic pressure for 1 hour. The expression of PDGF and PDGFR was evaluated using reverse transcriptase-polymerase chain reaction and Western bl...    »
 
Journal title abbreviation:
J Urol 
Year:
2015 
Journal volume:
194 
Journal issue:
Pages contribution:
1797-805 
Language:
eng 
Print-ISSN:
0022-5347 
TUM Institution:
Klinik für Anästhesiologie