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Document type:
journal article 
Author(s):
Luck, T; Riedel-Heller, S G; Luppa, M; Wiese, B; Köhler, M; Jessen, F; Bickel, H; Weyerer, S; Pentzek, M; König, H-H; Prokein, J; Ernst, A; Wagner, M; Mösch, E; Werle, J; Fuchs, A; Brettschneider, C; Scherer, M; Maier, W 
Title:
Apolipoprotein E epsilon 4 genotype and a physically active lifestyle in late life: analysis of gene-environment interaction for the risk of dementia and Alzheimer's disease dementia. 
Abstract:
As physical activity may modify the effect of the apolipoprotein E (APOE) ?4 allele on the risk of dementia and Alzheimer's disease (AD) dementia, we tested for such a gene-environment interaction in a sample of general practice patients aged ?75 years.Data were derived from follow-up waves I-IV of the longitudinal German study on Ageing, Cognition and Dementia in Primary Care Patients (AgeCoDe). The Kaplan-Meier survival method was used to estimate dementia- and AD-free survival times. Multivar...    »
 
Journal title abbreviation:
Psychol Med 
Year:
2014 
Journal volume:
44 
Journal issue:
Pages contribution:
1319-29 
Language:
eng 
Print-ISSN:
0033-2917 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie