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Document type:
journal article
Author(s):
Wason, James M S, JM; Stecher, Lynne, L; Mander, Adrian P, AP
Title:
Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?
Abstract:
Multi-arm trials enable the evaluation of multiple treatments within a single trial. They provide a way of substantially increasing the efficiency of the clinical development process. However, since multi-arm trials test multiple hypotheses, some regulators require that a statistical correction be made to control the chance of making a type-1 error (false-positive). Several conflicting viewpoints are expressed in the literature regarding the circumstances in which a multiple-testing correction s...     »
Journal title abbreviation:
Trials
Year:
2014
Journal volume:
15
Pages contribution:
364
Language:
eng
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/25230772
TUM Institution:
Institut für Medizinische Statistik und Epidemiologie
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