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Document type:
journal article 
Author(s):
Knolle, Percy A 
Title:
Hitting the right button: MAVS-mediated defense against HAV infection. 
Abstract:
Studying the immune response against infection with hepatitis viruses is hampered by the lack of suitable preclinical model systems. A recent publication in Science identifies the cytosolic adapter molecule MAVS as being responsible for species restriction of infection with hepatitis A virus as well as linking cytosolic immune sensing in infected hepatocytes with innate effector functions and protective adaptive immunity. 
Journal title abbreviation:
Cell Res 
Year:
2017 
Journal volume:
27 
Journal issue:
Pages contribution:
7-8 
Language:
eng 
Print-ISSN:
1001-0602 
TUM Institution:
Institut für Molekulare Immunologie