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Document type:
journal article 
Author(s):
Höchst, Bastian; Knolle, Percy A 
Title:
Checkpoint Inhibition in Head and Neck Cancer: Immune Therapeutic Options, Limitations, and Beyond. 
Abstract:
The immune system functions to defend the organism against infectious microorganisms but also against transformed cells. This key role of the immune system, in particular cancer-specific T cells, in eliminating cancer cells is compromised by various immune escape strategies employed by cancer cells and the cancer microenvironment. Here, we review the current knowledge about the immune escape mechanisms of cancer and the attempts to reconstitute cancer-specific immunity by using checkpoint inhibi...    »
 
Journal title abbreviation:
ORL J Otorhinolaryngol Relat Spec 
Year:
2017 
Journal volume:
79 
Journal issue:
1-2 
Pages contribution:
24-33 
Language:
eng 
Print-ISSN:
0301-1569 
TUM Institution:
Institut für Molekulare Immunologie