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Document type:
journal article 
Author(s):
Höfelmann, D; di Benedetto, B; Azad, S C; Micale, V; Wotjak, C T; Rammes, G 
Title:
Lack of interaction of endocannabinoids and 5-HT(3) neurotransmission in associative fear circuits of the amygdala: evidence from electrophysiological and behavioural experiments. 
Abstract:
Both the serotonergic and the endocannabinoid system play a major role in mediating fear and anxiety. In the basolateral amygdala (BLA) it has been shown that the cannabinoid receptor 1 (CB1) is highly co-expressed with 5-HT3 receptors on GABAergic interneurons suggesting that 5-HT3 receptor activity modulates CB1-mediated effects on inhibitory synaptic transmission. In the present study, we investigated the possible interactions of CB1 and 5-HT3-mediated neuronal processes in the BLA using elec...    »
 
Journal title abbreviation:
Brain Res 
Year:
2013 
Journal volume:
1527 
Pages contribution:
47-56 
Language:
eng 
Print-ISSN:
0006-8993 
TUM Institution:
Klinik für Anästhesiologie