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Document type:
journal article 
Author(s):
Grundmann, Sebastian; Lindmayer, Christian; Hans, Felix P; Hoefer, Imo; Helbing, Thomas; Pasterkamp, Gerard; Bode, Christoph; de Kleijn, Dominique; Moser, Martin 
Title:
FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells. 
Abstract:
Forkhead box (Fox) transcription factors are important regulators of cardiovascular development and several Fox-proteins have recently been shown to modulate embryonic and post-natal angiogenesis. However, the role of the FoxP subfamily, which is highly expressed in cardiovascular tissue, has not been investigated so far. Here, we show that the transcription factor FoxP1 is the highest expressed FoxP-protein in endothelial cells and that it is upregulated at the site of neovascularization during...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2013 
Journal volume:
Journal issue:
Pages contribution:
e70873 
Language:
eng 
TUM Institution:
Klinik für Anästhesiologie