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Author(s):
Roth, Susanne; Thomas, Christina; Ruland, Jürgen; Hartmann, G.; Wagner, H.
Title:
Immunobiology of C-Type Lectin Receptors
Abstract:
C-type lectin receptors (CLRs) that signal via the kinase Syk are an important class of pattern recognition receptors in the innate immune system. They recognize pathogen- and host-derived danger signals, and are best known for their role in antifungal immunity. Here, we review recent insights into the molecular mechanisms of CLR signaling, and their significance in host defense.
Journal title:
Else Kröner-Fresenius Symposia
Year:
2013
Journal volume:
4
Pages contribution:
11--14
Fulltext / DOI:
doi:10.1159/000346538
Publisher:
S. Karger AG
Publisher address:
Basel, Switzerland
Print-ISSN:
1663-0114
E-ISSN:
1663-0122
Notes:
Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG-geförderten) Allianz- bzw. Nationallizenz frei zugänglich. This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.
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