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Document type:
journal article 
Author(s):
Schmitt, MM; Megens, RT; Zernecke, A; Bidzhekov, K; van den Akker, NM; Rademakers, T; van Zandvoort, MA; Hackeng, TM; Koenen, RR; Weber, C 
Title:
Endothelial junctional adhesion molecule-a guides monocytes into flow-dependent predilection sites of atherosclerosis. 
Abstract:
Junctional adhesion molecule (JAM)-A expressed in endothelial, epithelial, and blood cells can regulate permeability and leukocyte extravasation. Atherosclerosis develops at sites of disturbed flow in large arteries, but the mechanisms guiding inflammatory cells into these predilection sites remain unknown.To characterize cell-specific functions of JAM-A in atherosclerosis, we used apolipoprotein E-deficient mice with a somatic or endothelium-specific deficiency in JAM-A and bone marrow chimeras...    »
 
Journal title abbreviation:
Circulation 
Year:
2014 
Journal volume:
129 
Journal issue:
Pages contribution:
66-76 
Language:
eng 
Print-ISSN:
0009-7322 
TUM Institution:
Klinik für Gefäßchirurgie