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Document type:
journal article 
Author(s):
Schweneker, Katrin; Clemm, Christoph; Brügel, Melanie; Souvatzoglou, Michael; Hermisson, Mirjam; Schmidt-Graf, Friederike; Zimmer, Claus; Peschel, Christian; Jost, Philipp J 
Title:
Effective long-term treatment with bevacizumab for relapsed glioblastoma: case report and review of the literature. 
Abstract:
Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Despite the use of optimized first-line therapy, GBM is still associated with a poor prognosis and an effective second-line therapy remains an important challenge in this patient population. In 2009, the US Food and Drug Administration (FDA) approved the monoclonal anti-VEGF-antibody bevacizumab for the treatment of relapsed GBM after two phase-II studies showed its efficacy and safety, alone or in combinat...    »
 
Journal title abbreviation:
Exp Hematol Oncol 
Year:
2014 
Journal volume:
Pages contribution:
29 
Language:
eng 
TUM Institution:
III. Medizinische Klinik und Poliklinik; Neurologische Klinik und Poliklinik