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Dokumenttyp:
journal article 
Autor(en):
Tóth, V; Förschler, A; Hirsch, NM; den Hollander, J; Kooijman, H; Gempt, J; Ringel, F; Schlegel, J; Zimmer, C; Preibisch, C 
Titel:
MR-based hypoxia measures in human glioma. 
Abstract:
Hypoxia plays a central role in tumor stem cell genesis and is related to a more malignant tumor phenotype, therapy resistance (e.g. in anti-angiogenic therapies) and radio-insensitivity. Reliable hypoxia imaging would provide crucial metabolic information in the diagnostic work-up of brain tumors. In this study, we applied a novel BOLD-based MRI method for the measurement of relative oxygen extraction fraction (rOEF) in glioma patients and investigated potential benefits and drawbacks. Forty-fi...    »
 
Zeitschriftentitel:
J Neurooncol 
Jahr:
2013 
Band / Volume:
115 
Heft / Issue:
Seitenangaben Beitrag:
197-207 
Sprache:
eng 
Print-ISSN:
0167-594X 
TUM Einrichtung:
Abteilung für Neuroradiologie; Neurochirurgische Klinik und Poliklinik; Institut für Allgemeine Pathologie und pathologische Anatomie