Assessment of T1, T1?, and T2 values of the ulnocarpal disc in healthy subjects at 3 tesla.

Rauscher, Isabel; Bender, Benjamin; Grözinger, Gerd; Luz, Oliver; Pohmann, Rolf; Erb, Michael; Schick, Fritz; Martirosian, Petros

doi:10.1016/j.mri.2014.05.010

2014

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Titel:: Assessment of T1, T1?, and T2 values of the ulnocarpal disc in healthy subjects at 3 tesla.
Dokumenttyp:: Journal Article
Autor(en):: Rauscher, Isabel; Bender, Benjamin; Grözinger, Gerd; Luz, Oliver; Pohmann, Rolf; Erb, Michael; Schick, Fritz; Martirosian, Petros
Abstract:: The purpose of this study was to implement clinically feasible imaging techniques for determination of T1, T1?, and T2 values of the ulnocarpal disc and to assess those values in a cohort of asymptomatic subjects at 3 tesla. Resulting values were compared between different age groups, since former histological findings of the ulnocarpal disc indicated frequent early degenerative changes of this tissue starting in the third decade of life, even in asymptomatic subjects.Twenty-seven healthy subjects were included in this study. T1 measurements were performed using 3D spoiled gradient-echo (GRE) sequence with variable flip angle. A series of T1? and T2-weighted images was acquired by a 3D GRE sequence after suitable magnetization preparation. T1,T1?, and T2 maps of the ulnocarpal disc were calculated pixel-wise. Representative mean values from extended regions were analysed.Mean T1 values of the ulnocarpal disc ranged from 722 ms in a 39 year-old subject to 1264 ms in a 65 year-old subject, T1? ranged from 9.2 ms (26 year-old subject) to 25.9 ms (65 year-old subject). Calculated T2 values showed a large range from 4.1 ms to 22.3 ms. T1? and T1 values tended to increase with age (p<0.05), whereas T2 did not.MR relaxometry of the ulnocarpal disc is feasible, and T1,T1?, and T2 values show modest variance in asymptomatic subjects. The potential of relaxation mapping to reveal relevant structural changes in patients has to be investigated in further studies.
Zeitschriftentitel:: Magn Reson Imaging
Jahr:: 2014
Band / Volume:: 32
Heft / Issue:: 9
Seitenangaben Beitrag:: 1085-90
Sprache:: eng
Volltext / DOI:: doi:10.1016/j.mri.2014.05.010
PubMed:: http://view.ncbi.nlm.nih.gov/pubmed/24960365
Print-ISSN:: 0730-725X
TUM Einrichtung:: Klinik und Poliklinik für Nuklearmedizin
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mediaTUM Gesamtbestand Einrichtungen Schools TUM School of Medicine and Health Departments Clinical Medicine Klinik und Poliklinik für Nuklearmedizin (Prof. Weber)2014