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Dokumenttyp:
journal article 
Autor(en):
Steinmann, P; Walters, DK; Arlt, MJ; Banke, IJ; Ziegler, U; Langsam, B; Arbiser, J; Muff, R; Born, W; Fuchs, B 
Titel:
Antimetastatic activity of honokiol in osteosarcoma. 
Abstract:
Metastasizing osteosarcoma has a mean 5-year survival rate of only 20% to 30%. Therefore, novel chemotherapeutics for more effective treatment of this disease are required.The antineoplastic activity of honokiol, which was demonstrated previously in numerous malignancies, was studied in vivo in C3H mice subcutaneously injected with syngeneic ?-galactosidase bacterial gene (lacZ)-expressing LM8 osteosarcoma (LM8-lacZ) cells. In vitro cytotoxic effects of honokiol were investigated in 8 human and...    »
 
Zeitschriftentitel:
Cancer 
Jahr:
2012 
Band / Volume:
118 
Heft / Issue:
Seitenangaben Beitrag:
2117-27 
Sprache:
eng 
Print-ISSN:
0008-543X 
TUM Einrichtung:
r Unfallchirurgie; dische Klinik und Poliklinik